| CAS | 348603-19-0 |
| Sequence | Ac-Asp-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr(SO3H)-Leu-Gln-OH |
| Sequence Single | Ac-DGDFEEEIPEEY(SO3H)LQ |
| Molecular Formula | C72H100N14O32S |
| Molecular Weight | 1705.73 |
| Synonyms | Hirugen |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Hematology |
| Description | Acetyl-Hirudin (53-65) (sulfated) also called hirugen, is the C-terminal fragment of hirudin (residues 53-65), it binds to and thereby protects thrombin against cleavage by trypsin, and to a lesser degree prevents the cleavage of thrombin by pancreatic elastase. |
| References | 1. Angiotensin I-converting enzyme inhibitory peptides derived from bonito bowels autolysate. N.Matsumura et al., Biosci. Biotechnol. Biochem., 57, 695 (1993) 2. Inhibition of thrombin by synthetic hirudin peptides. C.G.Binnie et al., FEBS Lett., 270, 85 (1990) |
Acetyl-Hirudin (53-65) (sulfated)
CAS No.: 348603-19-0
Acetyl-Hirudin (53-65) (sulfated) also called hirugen, is the C-terminal fragment of hirudin (residues 53-65), it binds
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