| CAS | 186901-17-7 |
| Sequence | H-Arg-Arg-Ala-Ala-Glu-Glu-Leu-Asp-Ser-Arg-Ala-Gly-pSer-Pro-Gln-Leu-OH |
| Sequence Single | RRAAEELDSRAG-pSer-PQL |
| Molecular Formula | C71H123N26O29P |
| Molecular Weight | 1835.88 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Description | 2B-(SP) is a selective phosphopeptide substrate for glycogen synthase kinase-3 (GSK-3); derived from the phosphorylation site of the translation factor eIF2B. |
| References | 1. Peptide substrates suitable for assaying glycogen synthase kinase-3 in crude cell extracts. Welsh et al (1997). Anal.Biochem. 244 16 PMID: 9025901 2. Phosphorylated seryl and threonyl, but not tyrosyl, residues are efficient specificity determinants for GSK-3β and Shaggy. Williams et al (1999). FEBS Lett. 448 86 PMID: 10217415 |