trans-3,5-Dimethoxystilbene (cis-Pinosylvin dimethyl ether) is a naturally occurring compound extracted from the benzene extract of jack pine (Pinus bunksiuna) bark.

Physicochemical Properties

Molecular Formula	C16H16O2
Molecular Weight	240.2970
Exact Mass	240.115
CAS #	21956-56-9
PubChem CID	5316874
Appearance	Off-white to light yellow solid powder
Density	1.089g/cm3
Boiling Point	376.5ºC at 760mmHg
Flash Point	150.7ºC
Vapour Pressure	1.56E-05mmHg at 25°C
Index of Refraction	1.615
LogP	3.874
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	4
Heavy Atom Count	18
Complexity	244
Defined Atom Stereocenter Count	0
SMILES	O(C([H])([H])[H])C1C([H])=C(C([H])=C(/C(/[H])=C(\[H])/C2C([H])=C([H])C([H])=C([H])C=2[H])C=1[H])OC([H])([H])[H]
InChi Key	BIYGTLDPTJMNET-CMDGGOBGSA-N
InChi Code	InChI=1S/C16H16O2/c1-17-15-10-14(11-16(12-15)18-2)9-8-13-6-4-3-5-7-13/h3-12H,1-2H3/b9-8+
Chemical Name	1,3-dimethoxy-5-[(E)-2-phenylethenyl]benzene
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: This product requires protection from light (avoid light exposure) during transportation and storage.
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

Additional Infomation

(E)-3,5-Dimethoxystilbene is a stilbenoid. 3,5-Dimethoxystilbene has been reported in Gibbaria ilicifolia, Alpinia hainanensis, and other organisms with data available.

Solubility Data

Solubility (In Vitro)

DMSO : ~100 mg/mL (~416.15 mM)

Solubility (In Vivo)

Solubility in Formulation 1: ≥ 2.5 mg/mL (10.40 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	4.1615 mL	20.8073 mL	41.6146 mL
	5 mM	0.8323 mL	4.1615 mL	8.3229 mL
	10 mM	0.4161 mL	2.0807 mL	4.1615 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.