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rel-(2S,3R)-Voruciclib hydrochloride 1253647-46-9

rel-(2S,3R)-Voruciclib hydrochloride 1253647-46-9

CAS No.: 1253647-46-9

rel-(2S,3R)-VoruciclibHCl is an isomer of VoruciclibHCl. Voruciclib is an orally bioactive CDK inhibitor.
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rel-(2S,3R)-Voruciclib HCl is an isomer of Voruciclib HCl. Voruciclib is an orally bioactive CDK inhibitor.

Physicochemical Properties


CAS # 1253647-46-9
Appearance Typically exists as solid at room temperature
HS Tariff Code 2934.99.9001
Storage

Powder-20°C 3 years

4°C 2 years

In solvent -80°C 6 months

-20°C 1 month

Shipping Condition Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity


References

[1]. A synergistic pharmaceutical combination for the treatment of pancreatic cancer. WO2012123889A1.


Solubility Data


Solubility (In Vitro) DMSO : ≥ 250 mg/mL (493.78 mM)
Solubility (In Vivo) 10% DMSO+ 40% PEG300+ 5% Tween-80+ 45% saline : ≥ 2.08 mg/mL (4.11 mM) (Please use freshly prepared in vivo formulations for optimal results.)