p21PBP, a 20 amino acid peptide, is an inhibitor of DNA replication. p21PBP specifically binds to proliferating cell nuclear antigen (PCNA) purified from tumor cell extracts. p21PBP has the potential to be used in cancer research.

Physicochemical Properties

Molecular Formula	C112H181N37O30S
Molecular Weight	2557.93
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. A small peptide inhibitor of DNA replication defines the site of interaction between the cyclin-dependent kinase inhibitor p21WAF1 and proliferating cell nuclear antigen. Curr Biol. 1995 Mar 1;5(3):275-82.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	0.3909 mL	1.9547 mL	3.9094 mL
	5 mM	0.0782 mL	0.3909 mL	0.7819 mL
	10 mM	0.0391 mL	0.1955 mL	0.3909 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.