m3227G(5)ppp(5')m6Am triammonium is the triammonium salt form of m3227G(5)ppp(5')m6Am. m3227G(5)ppp(5')m6Am triammonium is a specific mRNA molecular structure consisting of a 3227-methylguanine (m3227G) cap, a triphosphate group, and N6,2'-O-dimethyladenosine. m6Am is a reversible modification located on the first coding nucleotide near the 5' cap of mRNA that affects the stability of mRNA.

Physicochemical Properties

Molecular Formula	C25H46N13O17P3
Molecular Weight	893.63
Related CAS #	m3227G(5)ppp(5')m6Am
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Reversible methylation of m6Am in the 5' cap controls mRNA stability. Nature. 2017 Jan 19;541(7637):371-375.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	1.1190 mL	5.5952 mL	11.1903 mL
	5 mM	0.2238 mL	1.1190 mL	2.2381 mL
	10 mM	0.1119 mL	0.5595 mL	1.1190 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.