m3227G(5)ppp(5')Am triammonium is the triammonium salt form of m3227G(5)ppp(5')Am. m3227G(5)ppp(5')Am is a special mRNA molecular structure consisting of a 3227-methylguanine (m3227G) cap, a triphosphate group and a 2'-O-methyladenosine. Am is a reversible modification located on the first coding nucleotide near the 5' cap end of mRNA, which can affect the stability of mRNA.

Physicochemical Properties

Molecular Formula	C24H44N13O17P3
Molecular Weight	879.60
Related CAS #	m3227G(5)ppp(5')Am;178422-14-5
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Reversible methylation of m6Am in the 5' cap controls mRNA stability. Nature. 2017 Jan 19;541(7637):371-375.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	1.1369 mL	5.6844 mL	11.3688 mL
	5 mM	0.2274 mL	1.1369 mL	2.2738 mL
	10 mM	0.1137 mL	0.5684 mL	1.1369 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.