m3227G(5)ppp(5')A is a specific mRNA molecular structure consisting of a 3227-methylguanine (m3227G) cap, a triphosphate group, and adenosine. m3227G(5)ppp(5')A affects the stability and translation efficiency of mRNA.

Physicochemical Properties

Molecular Formula	C23H33N10O17P3
Molecular Weight	814.49
CAS #	123212-19-1
Related CAS #	m3227G(5)ppp(5')A triammonium
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Reversible methylation of m6Am in the 5' cap controls mRNA stability. Nature. 2017 Jan 19;541(7637):371-375.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	1.2278 mL	6.1388 mL	12.2776 mL
	5 mM	0.2456 mL	1.2278 mL	2.4555 mL
	10 mM	0.1228 mL	0.6139 mL	1.2278 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.