cTEV6-2 binds to the cysteine residue (C151) of tobacco etch virus protease (TEV protease) and covalently inhibits TEV protease with an IC50 of 81.7 nM.

Physicochemical Properties

Molecular Formula	C63H93N17O22S3
Molecular Weight	1536.71
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Discovery of Thioether-Cyclized Macrocyclic Covalent Inhibitors by mRNA Display. J Am Chem Soc. 2024 Aug 28;146(34):24053-24060.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	0.6507 mL	3.2537 mL	6.5074 mL
	5 mM	0.1301 mL	0.6507 mL	1.3015 mL
	10 mM	0.0651 mL	0.3254 mL	0.6507 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.