Beta-Cyfluthrin (beta-Cyfluthrin) is a type II synthetic pyrethroid and the active ingredient in many insecticide products used in agriculture to treat insect pests. β-Cyfluthrin is a neurotoxicant that affects calcium concentration in neural tissue by inhibiting Ca2+ ATPase, which is involved in calcium transport.

Physicochemical Properties

Molecular Formula	C22H18CL2FNO3
Molecular Weight	434.287627696991
Exact Mass	433.064
CAS #	1820573-27-0
Related CAS #	Cyfluthrin;68359-37-5
PubChem CID	56608859
Appearance	White to off-white solid powder
LogP	6.2
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	7
Heavy Atom Count	29
Complexity	679
Defined Atom Stereocenter Count	2
SMILES	Cl/C(=C\C1[C@H](C(=O)O[C@@H](C#N)C2C=CC(=C(C=2)OC2C=CC=CC=2)F)C1(C)C)/Cl
InChi Key	QQODLKZGRKWIFG-RUTXASTPSA-N
InChi Code	InChI=1S/C22H18Cl2FNO3/c1-22(2)15(11-19(23)24)20(22)21(27)29-18(12-26)13-8-9-16(25)17(10-13)28-14-6-4-3-5-7-14/h3-11,15,18,20H,1-2H3/t15?,18-,20+/m0/s1
Chemical Name	[(R)-cyano-(4-fluoro-3-phenoxyphenyl)methyl] (1S)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

Targets	Target: Ca2+ ATPase[1]
References	[1]. Effect of β-cyfluthrin (Synthetic Pyrethroid) on Learning, Muscular Coordination and Oxidative Stress in Swiss Albino Mice. Toxicol Ind Health. 2019 May;35(5):358-367.
Additional Infomation	See also: Cyfluthrin (annotation moved to).

Solubility Data

Solubility (In Vitro)

DMSO: 50 mg/mL (115.13 mM)

Solubility (In Vivo)

Solubility in Formulation 1: 2.5 mg/mL (5.76 mM) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), suspension solution; with sonication. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. Solubility in Formulation 2: ≥ 2.5 mg/mL (5.76 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	2.3026 mL	11.5130 mL	23.0261 mL
	5 mM	0.4605 mL	2.3026 mL	4.6052 mL
	10 mM	0.2303 mL	1.1513 mL	2.3026 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.