PeptideDB

α,β-MTDP trisodium 71370-60-0

α,β-MTDP trisodium 71370-60-0

CAS No.: 71370-60-0

α,β-MTDP trisodium is a thymidylate analog and a thymidine kinase inhibitor with a Ki of 23 µM.
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This product is for research use only, not for human use. We do not sell to patients.

α,β-MTDP trisodium is a thymidylate analog and a thymidine kinase inhibitor with a Ki of 23 µM.

Physicochemical Properties


Molecular Formula C11H15N2NA3O10P2
Molecular Weight 466.16
CAS # 71370-60-0
SMILES

P(CP(=O)([O-])[O-])(=O)([O-])OC[C@@H]1[C@H](C[C@H](N2C(NC(C(C)=C2)=O)=O)O1)O.[Na+].[Na+].[Na+]

Storage

Powder-20°C 3 years

4°C 2 years

In solvent -80°C 6 months

-20°C 1 month

Shipping Condition Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity


References

[1]. Effect of thymidine and thymidylate analogs on nucleic acid synthesis in tumor cells. Gan. 1977 Apr;68(2):159-63.


Solubility Data


Preparing Stock Solutions 1 mg 5 mg 10 mg
1 mM 2.1452 mL 10.7259 mL 21.4519 mL
5 mM 0.4290 mL 2.1452 mL 4.2904 mL
10 mM 0.2145 mL 1.0726 mL 2.1452 mL
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.