Zinc sulfate heptahydrate is a hydrate, the heptahydrate form of zinc sulfate. Zinc sulfate heptahydrate is a dietary supplement indicated for zinc deficiency and prevention of zinc deficiency in high-risk populations.

Physicochemical Properties

Molecular Formula	H14O11SZN
Molecular Weight	287.55
Exact Mass	285.954
CAS #	7446-20-0
Related CAS #	7733-02-0 (Parent);23713-49-7 (Parent)
PubChem CID	62640
Appearance	White to off-white solid powder
Density	1.957
Boiling Point	330ºC at 760 mmHg
Melting Point	100 °C
Hydrogen Bond Donor Count	7
Hydrogen Bond Acceptor Count	11
Rotatable Bond Count	0
Heavy Atom Count	13
Complexity	62.2
Defined Atom Stereocenter Count	0
InChi Key	RZLVQBNCHSJZPX-UHFFFAOYSA-L
InChi Code	InChI=1S/H2O4S.7H2O.Zn/c1-5(2,3)4;;;;;;;;/h(H2,1,2,3,4);7*1H2;/q;;;;;;;;+2/p-2
Chemical Name	zinc;sulfate;heptahydrate
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment, avoid exposure to moisture.
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

ln Vitro	Zinc supplementation can be achieved with zinc sulfate heptahydrate. Overdosing may cause fatigue, headaches, vomiting fits, and stomach pain.
References	[1]. Targeted Metabolomics of Xylose-Fermenting Yeasts Based on Mass Spectrometry.Methods Mol Biol. 2019;1859:155-169. [2]. Acceleration of healing with zinc sulfate. Ann Surg. 1967 Mar;165(3):432-6.
Additional Infomation	Zinc sulfate heptahydrate is a hydrate that is the heptahydrate form of zinc sulfate. It is a hydrate and a metal sulfate. It contains a zinc sulfate. See also: Zinc Cation (has active moiety) ... View More ...

Solubility Data

Solubility (In Vitro)

H2O: 166.67 mg/mL (579.62 mM)

Solubility (In Vivo)

Solubility in Formulation 1: ≥ 2.5 mg/mL (8.69 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 2.5 mg/mL (8.69 mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. Solubility in Formulation 3: ≥ 2.5 mg/mL (8.69 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	3.4777 mL	17.3883 mL	34.7766 mL
	5 mM	0.6955 mL	3.4777 mL	6.9553 mL
	10 mM	0.3478 mL	1.7388 mL	3.4777 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.