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VcMMAE-Deruxtecan is a drug-linker conjugate for ADC, which is formed by coupling linker with toxic molecules MMAE (microtubule inhibitor) and Exatecan (DNA topoisomerase I inhibitor). VcMMAE-Deruxtecan can be used for the synthesis of ADC.
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Physicochemical Properties
| Molecular Formula |
C121H159FN20O28
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| Molecular Weight |
2360.67
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| CAS # |
2760408-75-9
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| Synonyms |
SMP-54418
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| Storage |
Powder-20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
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| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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Biological Activity
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Solubility Data
| Preparing Stock Solutions |
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1 mg |
5 mg |
10 mg |
| 1 mM |
0.4236 mL |
2.1180 mL |
4.2361 mL |
| 5 mM |
0.0847 mL |
0.4236 mL |
0.8472 mL |
| 10 mM |
0.0424 mL |
0.2118 mL |
0.4236 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles. |
