VEGFR-2-IN-41 (Compound 8) is a VEGFR-2 inhibitor with IC50 of 0.0554 μM. VEGFR-2-IN-41 can induce cell apoptosis. VEGFR-2-IN-41 has anti-tumor activity.

Physicochemical Properties

Molecular Formula	C22H28N4O2S2
Molecular Weight	444.61
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

Targets	VEGFR-2 0.0554 μM (IC50)
References	[1]. Design, synthesis, and anticancer evaluation of N-sulfonylpiperidines as potential VEGFR-2 inhibitors, apoptotic inducers. Bioorg Chem. 2024 Feb 7;145:107157.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	2.2492 mL	11.2458 mL	22.4916 mL
	5 mM	0.4498 mL	2.2492 mL	4.4983 mL
	10 mM	0.2249 mL	1.1246 mL	2.2492 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.