PeptideDB

Utibaprilat 109683-79-6

Utibaprilat 109683-79-6

CAS No.: 109683-79-6

Utibaprilat is an ACE inhibitor and the major degradation product of Utibapril.
Data collection:peptidedb@qq.com

This product is for research use only, not for human use. We do not sell to patients.

Utibaprilat is an ACE inhibitor and the major degradation product of Utibapril.

Physicochemical Properties


Molecular Formula C20H27N3O5S
Molecular Weight 421.51
CAS # 109683-79-6
SMILES

OC([C@@H](N[C@H](C(N1N=C(C(C)(C)C)S[C@H]1C(=O)O)=O)C)CCC1=CC=CC=C1)=O

Synonyms

Utiprilat; FPL 63674XX
Storage

Powder-20°C 3 years

4°C 2 years

In solvent -80°C 6 months

-20°C 1 month

Shipping Condition Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity


References

[1]. Bioisosteric similarity of molecules based on structural alignment and observed chemical replacements in drugs. J Chem Inf Model. 2009 May;49(5):1280-97.

[2]. HPLC Determination of Utibapril and its Diacid FPL 63674XX in Rodent Laboratory Diet Using Selective Extraction and Gradient Elution Chromatography. Journal of liquid chromatography, 1991, 14(15): 2979-2991.


Solubility Data


Preparing Stock Solutions 1 mg 5 mg 10 mg
1 mM 2.3724 mL 11.8621 mL 23.7242 mL
5 mM 0.4745 mL 2.3724 mL 4.7448 mL
10 mM 0.2372 mL 1.1862 mL 2.3724 mL
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.