The binding affinity of trichilinin D to HSP90AA1, IL-6, mTOR, EGFR, CASP3 and HIF1A was evaluated to be -8.2, -7.5, -9.5, -8.3 -7.3 and -8.2 kcal/mol, respectively.

Physicochemical Properties

Molecular Formula	C37H44O8
Molecular Weight	616.74
CAS #	220698-24-8
SMILES	O1C[C@]2(C)[C@@H](C[C@@H]([C@]3(C)[C@H]4C[C@@H]([C@@]5(C)[C@H](C6=COC=C6)CC=C5[C@]4(C)[C@@H]([C@H]1[C@H]32)O)OC(C)=O)OC(/C=C/C1C=CC=CC=1)=O)O
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

Targets

IL-6 HSP90α

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	1.6214 mL	8.1071 mL	16.2143 mL
	5 mM	0.3243 mL	1.6214 mL	3.2429 mL
	10 mM	0.1621 mL	0.8107 mL	1.6214 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.