 Chemical Structure.png)
Physicochemical Properties
| Molecular Formula | C5H10O4 |
| Molecular Weight | 134.13 |
| Exact Mass | 134.057 |
| CAS # | 533-67-5 |
| Related CAS # | Thyminose-13C;478511-57-8;Thyminose-13C-1;478511-60-3;Thyminose-13C-2;159838-86-5;Thyminose-d2;478511-68-1;Thyminose-d3 |
| PubChem CID | 5460005 |
| Appearance | White to yellow solid powder |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 379.7±42.0 °C at 760 mmHg |
| Melting Point | 89-90 °C(lit.) |
| Flash Point | 197.6±24.4 °C |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.500 |
| LogP | -2.39 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 4 |
| Heavy Atom Count | 9 |
| Complexity | 83 |
| Defined Atom Stereocenter Count | 2 |
| SMILES | C(C=O)[C@@H]([C@@H](CO)O)O |
| InChi Key | ASJSAQIRZKANQN-CRCLSJGQSA-N |
| InChi Code | InChI=1S/C5H10O4/c6-2-1-4(8)5(9)3-7/h2,4-5,7-9H,1,3H2/t4-,5+/m0/s1 |
| Chemical Name | (3S,4R)-3,4,5-trihydroxypentanal |
| HS Tariff Code | 2934.99.9001 |
| Storage |
Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment (e.g. under nitrogen), avoid exposure to moisture. |
| Shipping Condition | Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs) |
Biological Activity
| Targets | Human Endogenous Metabolite |
| Additional Infomation |
2-deoxy-D-ribose is a deoxypentose that is D-ribose in which the hydroxy group at position C-2 is replaced by hydrogen. It has a role as a human metabolite, a Saccharomyces cerevisiae metabolite and a mouse metabolite. It is functionally related to a D-ribose. Deoxyribose is a metabolite found in or produced by Escherichia coli (strain K12, MG1655). 2-Deoxy-D-ribose has been reported in Homo sapiens and Trypanosoma brucei with data available. 2-deoxy-D-ribose is a metabolite found in or produced by Saccharomyces cerevisiae. |
Solubility Data
| Solubility (In Vitro) |
DMSO: 100 mg/mL (745.55 mM) H2O: 100 mg/mL (745.55 mM) |
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 2.5 mg/mL (18.64 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 2.5 mg/mL (18.64 mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. Solubility in Formulation 3: ≥ 2.5 mg/mL (18.64 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly. Solubility in Formulation 4: 50 mg/mL (372.77 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with ultrasonication. (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 7.4555 mL | 37.2773 mL | 74.5545 mL | |
| 5 mM | 1.4911 mL | 7.4555 mL | 14.9109 mL | |
| 10 mM | 0.7455 mL | 3.7277 mL | 7.4555 mL |