Tetradecyltrimethylammonium bromide, an organic structural unit, is a cationic surfactant with an asymmetric structure.

Physicochemical Properties

Molecular Formula	C17H38BRN
Molecular Weight	336.39
Exact Mass	335.218
CAS #	1119-97-7
Related CAS #	Tetradecyltrimethylammonium-d29 bromide;95523-73-2;Tetradecyltrimethylammonium-d38 bromide;95523-72-1
PubChem CID	14250
Appearance	White to off-white solid powder
Melting Point	245-250 °C(lit.)
LogP	6.351
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	13
Heavy Atom Count	19
Complexity	158
Defined Atom Stereocenter Count	0
InChi Key	CXRFDZFCGOPDTD-UHFFFAOYSA-M
InChi Code	InChI=1S/C17H38N.BrH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18(2,3)4;/h5-17H2,1-4H3;1H/q+1;/p-1
Chemical Name	trimethyl(tetradecyl)azanium;bromide
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment (e.g. under nitrogen), avoid exposure to moisture and light.
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

ln Vitro	In capillary electrophoresis, tetradecyltrimethylammonium bromide (TTAB; TTABr) is being used more frequently as a surface active aid to help separate anionic species derived from acids. For optimal effects, tetradecyltrimethylammonium bromide has been found to need a minimum concentration of about 0.4 mM. This concentration has been selected because it is near the critical micelle concentration (CMC), which is thought to be necessary for the formation of "hemimicelles" on the capillary inner wall[3].
References	[1]. The effect of molecular structure on the surface properties of selected quaternary ammonium salts. J Colloid Interface Sci. 2008;321(1):220-226. [2]. Mixtures of Nonionic and Ionic Surfactants. The Effect of Counterion Binding in Mixtures of Tetradecyldimethylamine Oxide and Tetradecyltrimethylammonium Bromide. Langmuir 1994, 10, 8, 2594-2603. [3]. The surface properties of tetradecyltrimethylammonium bromide observed by capillary electrophoresis. J Chromatogr Sci. 2002;40(4):187-190.
Additional Infomation	Cetrimide is an organic molecular entity.

Solubility Data

Solubility (In Vitro)	H2O: 125 mg/mL (371.59 mM)
Solubility (In Vivo)	Solubility in Formulation 1: 50 mg/mL (148.64 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	2.9727 mL	14.8637 mL	29.7274 mL
	5 mM	0.5945 mL	2.9727 mL	5.9455 mL
	10 mM	0.2973 mL	1.4864 mL	2.9727 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.