T-22 ([Tyr5,12,Lys7]-Polyphemusin II) is a novel anti-HIV synthetic peptide with an EC50 of 0.008 μg/mL and a CC50 of 54 μg/mL. T22 promotes tomato plant height, photosynthesis, total chlorophyll content, and plant gas exchange, and is resistant to CMV.

Physicochemical Properties

Molecular Formula	C109H164N38O22S4
Molecular Weight	2486.97
CAS #	147658-54-6
SMILES	C(C1=CNC2C=CC=CC1=2)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@H]1CSSC[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@@]2([H])NC([C@@]([H])(NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@]([H])(CC3C=CC(O)=CC=3)NC(=O)[C@]([H])(CSSC2)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC2C=CC(O)=CC=2)NC1=O)CC1C=CC(O)=CC=1)=O)CC1C=CC(O)=CC=1)=O)CCCNC(N)=N)=O)CCCCN)=O)C(=O)N[C@H](C(=O)N)CCCNC(N)=N
Synonyms	[Tyr5,12,Lys7]-Polyphemusin II
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. A novel anti-HIV synthetic peptide, T-22 (Tyr5,12,Lys7-polyphemusin II). Biochemical and Biophysical Research Communications. Volume 189, Issue 2, 15 December 1992, Pages 845-850. [2]. Trichoderma harzianum T-22 Induces Systemic Resistance in Tomato Infected by Cucumber mosaic virus. Front Plant Sci. 2016 Oct 10:7:1520.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	0.4021 mL	2.0105 mL	4.0210 mL
	5 mM	0.0804 mL	0.4021 mL	0.8042 mL
	10 mM	0.0402 mL	0.2010 mL	0.4021 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.