Sodium oleate (sodium oleate) is the most common monounsaturated fertilizer sodium salt found in human fat cells and other tissues. Sodium oleate is a Na+/K+ ATPase activator.

Physicochemical Properties

Molecular Formula	C18H33NAO2
Molecular Weight	304.443
Exact Mass	304.237
CAS #	143-19-1
Related CAS #	Oleic acid;112-80-1
PubChem CID	23665730
Appearance	White to off-white solid powder
Density	0.9 g/cm3
Boiling Point	359.999ºC at 760 mmHg
Melting Point	232-235 °C(lit.)
Flash Point	270.099ºC
LogP	4.773
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	15
Heavy Atom Count	21
Complexity	239
Defined Atom Stereocenter Count	0
SMILES	CCCCCCCC/C=C\CCCCCCCC(=O)[O-].[Na+]
InChi Key	BCKXLBQYZLBQEK-KVVVOXFISA-M
InChi Code	InChI=1S/C18H34O2.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h9-10H,2-8,11-17H2,1H3,(H,19,20);/q;+1/p-1/b10-9-;
Chemical Name	sodium;(Z)-octadec-9-enoate
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment, avoid exposure to moisture.
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

ln Vitro	The most prevalent monounsaturated fertilizer (FA) in human fat cells and other tissues is oleic acid. In organs with high migration rates, oleic acid stimulates AMPK oil activation-mediated beta-oxidation, which in turn drives cell division and migration. Growth and death rates of low-proliferative tumors, including the MCF-7 cell line for breast cancer and the acid blocker SGC7901 [1].
References	[1]. High metastaticgastric and breast cancer cells consume oleic acid in an AMPK dependent manner. PLoS One. 2014 May 13;9(5):e97330. [2]. Activation of Na+/K(+)-ATPase by fatty acids, acylglycerols, and related amphiphiles: structure-activity relationship. Biochim Biophys Acta. 1996 Feb 21;1279(1):43-8.
Additional Infomation	Oleic acid, [sodium salt] is a light tan solid with a slight tallow-like odor. Sinks and mixes slowly with water. (USCG, 1999) Sodium oleate is an organic molecular entity.

Solubility Data

Solubility (In Vitro)	H2O : ~25 mg/mL (~82.12 mM) DMSO :< 1 mg/mL
Solubility (In Vivo)	Solubility in Formulation 1: 9.09 mg/mL (29.86 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication (<60°C).  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	3.2847 mL	16.4236 mL	32.8472 mL
	5 mM	0.6569 mL	3.2847 mL	6.5694 mL
	10 mM	0.3285 mL	1.6424 mL	3.2847 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.