SIRT1-IN-5 (215) is a NAD-dependent regulator of the protein deacetylase SIRT1.

Physicochemical Properties

Molecular Formula	C21H17N3O3S
Molecular Weight	391.44
CAS #	863589-21-3
SMILES	COC1=CC(=CC(=C1)C(=O)NC2=CC=CC(=C2)C3=NC4=C(S3)N=CC=C4)OC
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

Targets	SIRT1
References	[1]. Oxazolopyridine derivatives as sirtuin modulators. Patent WO2007019417A1.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	2.5547 mL	12.7733 mL	25.5467 mL
	5 mM	0.5109 mL	2.5547 mL	5.1093 mL
	10 mM	0.2555 mL	1.2773 mL	2.5547 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.