SEPT9-IN-1 (compound 8b) is a SEPT9 inhibitor with IC50 of 94.83 μM. SEPT9-IN-1 is cytotoxic to human oral squamous cell carcinoma cells with IC50 of 21 µM.

Physicochemical Properties

Molecular Formula	C26H30CLN3O3
Molecular Weight	467.99
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. The first attempt in synthesis, identification, and evaluation of SEPT9 inhibitors on human oral squamous carcinomas. Bioorg Chem. 2025 Jan:154:108068.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	2.1368 mL	10.6840 mL	21.3680 mL
	5 mM	0.4274 mL	2.1368 mL	4.2736 mL
	10 mM	0.2137 mL	1.0684 mL	2.1368 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.