(S)-3'-Aminoblebbistatin is a derivative of Blebbistatin. (S)-3'-Aminoblebbistatin has an inhibitory effect on myosin II with an IC50 of 14.1 µM.

Physicochemical Properties

Molecular Formula	C18H17N3O2
Molecular Weight	307.35
CAS #	2097141-18-7
SMILES	N1C2=C(C=C(C)C=C2)C(=O)[C@]2(O)CCN(C3=CC=CC(N)=C3)C=12
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Discovery of (S)-3'-hydroxyblebbistatin and (S)-3'-aminoblebbistatin: polar myosin II inhibitors with superior research tool properties. Org Biomol Chem. 2017 Mar 1;15(9):2104-2118.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	3.2536 mL	16.2681 mL	32.5362 mL
	5 mM	0.6507 mL	3.2536 mL	6.5072 mL
	10 mM	0.3254 mL	1.6268 mL	3.2536 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.