(S)-3'-Hydroxy blebbistatin is a myosin II inhibitor with better water solubility than blebbistatin.

Physicochemical Properties

Molecular Formula	C18H16N2O3
Molecular Weight	308.33
CAS #	2097136-42-8
SMILES	N1C2=C(C=C(C)C=C2)C(=O)[C@]2(O)CCN(C3=CC=CC(O)=C3)C=12
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Discovery of (S)-3'-hydroxyblebbistatin and (S)-3'-aminoblebbistatin: polar myosin II inhibitors with superior research tool properties. Org Biomol Chem. 2017 Mar 1;15(9):2104-2118.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	3.2433 mL	16.2164 mL	32.4328 mL
	5 mM	0.6487 mL	3.2433 mL	6.4866 mL
	10 mM	0.3243 mL	1.6216 mL	3.2433 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.