PeptideDB

Ruxolitinib intermediate 1236033-04-7

Ruxolitinib intermediate 1236033-04-7

CAS No.: 1236033-04-7

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For mo
Data collection:peptidedb@qq.com

This product is for research use only, not for human use. We do not sell to patients.

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.



Physicochemical Properties


Molecular Formula C41H46N6O9SI
Molecular Weight 794.924251079559
Exact Mass 794.309
CAS # 1236033-04-7
PubChem CID 134714823
Appearance Typically exists as solid at room temperature
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 13
Rotatable Bond Count 18
Heavy Atom Count 57
Complexity 1110
Defined Atom Stereocenter Count 3
SMILES

[C@H](C(=O)O)(OC(C1C=CC=CC=1)=O)[C@@H](C(=O)O)OC(C1C=CC=CC=1)=O.C(N1C=CC2=C(C3C=NN([C@@H](C4CCCC4)CC#N)C=3)N=CN=C12)OCC[Si](C)(C)C

InChi Key QSAALLKTEBWYGD-FFLVPEHISA-N
InChi Code

InChI=1S/C23H32N6OSi.C18H14O8/c1-31(2,3)13-12-30-17-28-11-9-20-22(25-16-26-23(20)28)19-14-27-29(15-19)21(8-10-24)18-6-4-5-7-18;19-15(20)13(25-17(23)11-7-3-1-4-8-11)14(16(21)22)26-18(24)12-9-5-2-6-10-12/h9,11,14-16,18,21H,4-8,12-13,17H2,1-3H3;1-10,13-14H,(H,19,20)(H,21,22)/t21-;13-,14-/m10/s1
Chemical Name

(3R)-3-cyclopentyl-3-[4-[7-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-d]pyrimidin-4-yl]pyrazol-1-yl]propanenitrile;(2S,3S)-2,3-dibenzoyloxybutanedioic acid
HS Tariff Code 2934.99.9001
Storage

Powder-20°C 3 years

4°C 2 years

In solvent -80°C 6 months

-20°C 1 month

Shipping Condition Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity



Solubility Data


Solubility (In Vitro) May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
Preparing Stock Solutions 1 mg 5 mg 10 mg
1 mM 1.2580 mL 6.2899 mL 12.5799 mL
5 mM 0.2516 mL 1.2580 mL 2.5160 mL
10 mM 0.1258 mL 0.6290 mL 1.2580 mL
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.