Rac1 Inhibitor W56 TFA is residues 45-60 in Rac1. Rac1 Inhibitor W56 TFA inhibits the interaction of Rac1 with the guanine nucleotide exchange factors TrioN, GEF-H1, and Tiam.

Physicochemical Properties

Molecular Formula	C76H118F3N19O25S
Molecular Weight	1785.95
Related CAS #	Rac1 Inhibitor W56;1095179-01-3
Appearance	White to off-white solid powder
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment, avoid exposure to moisture.
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Trp(56) of rac1 specifies interaction with a subset of guanine nucleotide exchange factors [published correction appears in J Biol Chem. 2005 Jan 14;280(2):1704]. J Biol Chem. 2001;276(50):47530-47541.

Solubility Data

Solubility (In Vitro)	H2O :~100 mg/mL (~55.99 mM)
Solubility (In Vivo)	Solubility in Formulation 1: 100 mg/mL (55.99 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	0.5599 mL	2.7996 mL	5.5993 mL
	5 mM	0.1120 mL	0.5599 mL	1.1199 mL
	10 mM	0.0560 mL	0.2800 mL	0.5599 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.