RS-15385-198 is an isomer of Delequamine (RS-15385-197). RS-15385-198 has a pKi of 6.32 for α2-adrenergic receptors in rat cortex. RS-15385-198 is an antagonist of UK-14304 in rat vas deferens and guinea pig ileum.

Physicochemical Properties

Molecular Formula	C18H26N2O3S
Molecular Weight	350.48
CAS #	121961-55-5
SMILES	N1(S(C)(=O)=O)[C@@]2([H])[C@]([H])(CN3CCC4=C([C@@]3([H])C2)C=CC(OC)=C4)CCC1
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. The pharmacology of RS-15385-197, a potent and selective alpha 2-adrenoceptor antagonist. Br J Pharmacol. 1993 Feb;108(2):516-25.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	2.8532 mL	14.2661 mL	28.5323 mL
	5 mM	0.5706 mL	2.8532 mL	5.7065 mL
	10 mM	0.2853 mL	1.4266 mL	2.8532 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.