Propane sultone is a versatile intermediate. Propane sultone can be used as an additive for lithium battery electrolytes. Propane sultone is combined with cellulose and carbohydrates and can be used in sizing, printing and textiles. Propane sultone can be used to make dyes.

Physicochemical Properties

Molecular Formula	C3H6O3S
Molecular Weight	122.14
CAS #	1120-71-4
Appearance	<30°C Solid powder,>33°C Liquid ; Colorless to off-white
Density	1.392
Boiling Point	180 ºC (30 mmHg)
Melting Point	30-33 °C(lit.)
Flash Point	110 ºC
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.478
LogP	-0.69
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Fischer R F. PropanesultoneJ. Industrial & Engineering Chemistry, 1964, 56(3): 41-45. [2]. Electrochemical reduction of 1, 3-propane sultone on graphite electrodes and its application in Li-ion batteriesJ. Electrochemical and solid-state letters, 2006, 9(4): A196.

Solubility Data

Solubility (In Vitro)

DMSO : ~200 mg/mL (~1637.47 mM; with ultrasonication)

Solubility (In Vivo)

Solubility in Formulation 1: ≥ 5 mg/mL (40.94 mM) (saturation unknown) in 10% DMSO 40% PEG300 5% Tween-80 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 50.0 mg/mL clear DMSO stock solution and add it to 400 μL PEG300 and mix well. Then add 50 μL Tween-80 to the above system and mix well. Then continue to add 450 μL of physiological saline to make up to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 5 mg/mL (40.94 mM) (saturation unknown) in 10% DMSO 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 50.0 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD in saline and mix well. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. Solubility in Formulation 3: ≥ 5 mg/mL (40.94 mM)(saturation unknown) in 10% DMSO 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), suspension solution. For example, if 1 mL of working solution is to be prepared, you can add 1 mL of working solution as an example, take 100 μL of 50.0 mg/mL clear DMSO stock solution and add it to 900 μL corn oil and mix well.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	8.1873 mL	40.9366 mL	81.8733 mL
	5 mM	1.6375 mL	8.1873 mL	16.3747 mL
	10 mM	0.8187 mL	4.0937 mL	8.1873 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.