Phosphorylcholine chloride (Phosphocholine chloride) is a component of lecithin that forms the outer structure of cell membranes and has good blood compatibility.

Physicochemical Properties

Molecular Formula	C5H15CLNO4P
Molecular Weight	219.60400
Exact Mass	219.042
CAS #	107-73-3
PubChem CID	7886
Appearance	Colorless to light yellow solid-liquid Mixture
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	4
Heavy Atom Count	12
Complexity	158
Defined Atom Stereocenter Count	0
SMILES	O=P(OCC[N+](C)(C)C)(O)O.[Cl-]
InChi Key	PYJNAPOPMIJKJZ-UHFFFAOYSA-N
InChi Code	InChI=1S/C5H14NO4P.ClH/c1-6(2,3)4-5-10-11(7,8)9;/h4-5H2,1-3H3,(H-,7,8,9);1H
Chemical Name	trimethyl(2-phosphonooxyethyl)azanium;chloride
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment, avoid exposure to moisture.
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

ln Vitro	Phosphorylcholine materials, which have a molecular replica of the main zwitterionic phospholipid headgroup present in the cell lipid membrane, are bioinspired polymers that resemble the extracellular surface of red blood cells. The PC-polymer's phosphorylcholine side chain includes the phosphate moiety found in phosphatidylcholine and phosphatidylserine, the latter of which is a membrane lipid component involved in biomineralization and capable of binding calcium[1].
References	[1]. The effect of cationically-modified phosphorylcholine polymers on human osteoblasts in vitro and their effect on bone formation in vivo. J Mater Sci Mater Med. 2017 Aug 17;28(9):144.
Additional Infomation	Phosphorylcholine chloride is an organic chloride salt comprising a choline phosphate cation and chloride anion. It contains a phosphocholine and a chloride. Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.

Solubility Data

Solubility (In Vitro)	H2O : ~250 mg/mL (~1138.43 mM)
Solubility (In Vivo)	Solubility in Formulation 1: 100 mg/mL (455.37 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	4.5537 mL	22.7687 mL	45.5373 mL
	5 mM	0.9107 mL	4.5537 mL	9.1075 mL
	10 mM	0.4554 mL	2.2769 mL	4.5537 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.