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Panaxatriol 32791-84-7

Panaxatriol 32791-84-7

CAS No.: 32791-84-7

Panaxatriol is a naturally occurring compound that can reduce bone marrow suppression caused by radiation damage.
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This product is for research use only, not for human use. We do not sell to patients.

Panaxatriol is a naturally occurring compound that can reduce bone marrow suppression caused by radiation damage.

Physicochemical Properties


Molecular Formula C30H52O4
Molecular Weight 476.73148
Exact Mass 476.386
CAS # 32791-84-7
PubChem CID 73599
Appearance White to off-white solid powder
Density 1.1±0.1 g/cm3
Boiling Point 561.5±50.0 °C at 760 mmHg
Flash Point 293.4±30.1 °C
Vapour Pressure 0.0±3.5 mmHg at 25°C
Index of Refraction 1.527
LogP 5.94
Hydrogen Bond Donor Count 3
Hydrogen Bond Acceptor Count 4
Rotatable Bond Count 1
Heavy Atom Count 34
Complexity 823
Defined Atom Stereocenter Count 11
InChi Key QFJUYMMIBFBOJY-UHFFFAOYSA-N
InChi Code

InChI=1S/C30H52O4/c1-25(2)12-9-13-30(8,34-25)18-10-15-28(6)23(18)19(31)16-21-27(5)14-11-22(33)26(3,4)24(27)20(32)17-29(21,28)7/h18-24,31-33H,9-17H2,1-8H3
Chemical Name

4,4,8,10,14-pentamethyl-17-(2,6,6-trimethyloxan-2-yl)-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,6,12-triol
HS Tariff Code 2934.99.9001
Storage

Powder-20°C 3 years

4°C 2 years

In solvent -80°C 6 months

-20°C 1 month

Shipping Condition Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity


References

[1]. Effect of panaxatriol on hematogenesis and granulocyte-macrophage colony stimulating factor in radiation injured mice. Saudi Med J. 2007 Dec;28(12):1791-5.

Additional Infomation Panaxatriol is a triterpenoid saponin.
Panaxatriol has been reported in Panax ginseng with data available.

Solubility Data


Solubility (In Vitro) DMSO : ~25 mg/mL (~52.44 mM)
Solubility (In Vivo) Solubility in Formulation 1: ≥ 2.5 mg/mL (5.24 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly.

 (Please use freshly prepared in vivo formulations for optimal results.)
Preparing Stock Solutions 1 mg 5 mg 10 mg
1 mM 2.0976 mL 10.4881 mL 20.9762 mL
5 mM 0.4195 mL 2.0976 mL 4.1952 mL
10 mM 0.2098 mL 1.0488 mL 2.0976 mL
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.