Palmitic acid-1-13C is a 13C (carbon 13)-labeled Palmitic acid. Palmitic acid A long-chain saturated fatty acid commonly found in animals and plants. Palmitic acid induces the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer-binding protein homologous protein (CHOP) in mouse granulosa cells.

Physicochemical Properties

Molecular Formula	C1513CH32O2
Molecular Weight	257.42
Exact Mass	257.244
CAS #	57677-53-9
Related CAS #	Palmitic acid;57-10-3;Palmitic acid sodium;408-35-5;Palmitic acid-1,2,3,4-13C4;287100-89-4
PubChem CID	9881577
Appearance	White to off-white solid powder
Density	0.855 g/mL at 25ºC
Boiling Point	271.5ºC100 mm Hg(lit.)
Melting Point	61-64ºC(lit.)
Index of Refraction	1.454
LogP	5.552
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	14
Heavy Atom Count	18
Complexity	178
Defined Atom Stereocenter Count	0
SMILES	CCCCCCCCCCCCCCC[13C](=O)O
InChi Key	IPCSVZSSVZVIGE-LOYIAQTISA-N
InChi Code	InChI=1S/C16H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h2-15H2,1H3,(H,17,18)/i16+1
Chemical Name	(113C)hexadecanoic acid
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Antitumor activity of palmitic acid found as a selective cytotoxic substance in a marine red alga. Anticancer Res. 2002 Sep-Oct;22(5):2587-90.

Solubility Data

Solubility (In Vitro)

DMSO : 66.67 mg/mL (258.99 mM)

Solubility (In Vivo)

Solubility in Formulation 1: ≥ 2.5 mg/mL (9.71 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	3.8847 mL	19.4235 mL	38.8470 mL
	5 mM	0.7769 mL	3.8847 mL	7.7694 mL
	10 mM	0.3885 mL	1.9424 mL	3.8847 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.