PeptideDB

PTAD-PEG8-azide

PTAD-PEG8-azide

CAS No.:

PTAD-PEG8-azide is a cleavable ADC linker containing an azide group that can be used to synthesize antibody-conjugated a
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PTAD-PEG8-azide is a cleavable ADC linker containing an azide group that can be used to synthesize antibody-conjugated active molecules (ADCs).

Physicochemical Properties


Molecular Formula C30H49N7O13
Molecular Weight 715.75
Appearance Solid-Liquid Mixture
Storage

Powder-20°C 3 years

4°C 2 years

In solvent -80°C 6 months

-20°C 1 month

Shipping Condition Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity


Targets Cleavable Linker
ln Vitro ADCs consist of an antibody that is linked to an ADC toxin molecule via an ADC linker.

Solubility Data


Solubility (In Vitro) DMSO : ~125 mg/mL (~174.64 mM; with ultrasonication)
Preparing Stock Solutions 1 mg 5 mg 10 mg
1 mM 1.3971 mL 6.9857 mL 13.9714 mL
5 mM 0.2794 mL 1.3971 mL 2.7943 mL
10 mM 0.1397 mL 0.6986 mL 1.3971 mL
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.