PPARα/γ/δ agonist 1 (Compound 2) is a potent PPARα/γ/δ agonist with IC50 of 70 nM for PPARγ. PPARα/γ/δ agonist 1 can be used in the study of type 2 diabetes.

Physicochemical Properties

Molecular Formula	C33H31NO5
Molecular Weight	521.60
CAS #	853652-40-1
SMILES	CCCC1=C(C=CC2=CC(=CC=C21)C(=O)C3=CC=CC=C3)OCCCOC4=CC=C5C(=C4)C=CN5CC(=O)O
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists. J Med Chem. 2006 Oct 19;49(21):6421-4.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	1.9172 mL	9.5859 mL	19.1718 mL
	5 mM	0.3834 mL	1.9172 mL	3.8344 mL
	10 mM	0.1917 mL	0.9586 mL	1.9172 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.