PDP-EA is a compound that increases FAAH (fatty acid amide hydrolase) amide hydrolase activity.

Physicochemical Properties

Molecular Formula	C25H43NO3
Molecular Weight	405.613827943802
Exact Mass	405.324
CAS #	861891-72-7
PubChem CID	69724031
Appearance	White to off-white solid powder
Density	1.0±0.1 g/cm3
Boiling Point	581.5±40.0 °C at 760 mmHg
Flash Point	305.5±27.3 °C
Vapour Pressure	0.0±1.7 mmHg at 25°C
Index of Refraction	1.500
LogP	8.35
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	19
Heavy Atom Count	29
Complexity	375
Defined Atom Stereocenter Count	0
SMILES	O=C(COC1C=C(CCCCCCCCCCCCCCC)C=CC=1)NCCO
InChi Key	BIOVSNWTCKRADD-UHFFFAOYSA-N
InChi Code	InChI=1S/C25H43NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-23-17-15-18-24(21-23)29-22-25(28)26-19-20-27/h15,17-18,21,27H,2-14,16,19-20,22H2,1H3,(H,26,28)
Chemical Name	N-(2-hydroxyethyl)-2-(3-pentadecylphenoxy)acetamide
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: This product requires protection from light (avoid light exposure) during transportation and storage.
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Synthesis of phenoxyacyl-ethanolamides and their effects on fatty acid amide hydrolase activity. J Biol Chem. 2014 Mar 28;289(13):9340-51.

Solubility Data

Solubility (In Vitro)

DMSO : ~50 mg/mL (~123.27 mM)

Solubility (In Vivo)

Solubility in Formulation 1: ≥ 1.25 mg/mL (3.08 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 12.5 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	2.4654 mL	12.3271 mL	24.6542 mL
	5 mM	0.4931 mL	2.4654 mL	4.9308 mL
	10 mM	0.2465 mL	1.2327 mL	2.4654 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.