Nepsilon-Acetyl-L-lysine is an analogue of the amino acid (AA) lysine.

Physicochemical Properties

Molecular Formula	C8H16N2O3
Molecular Weight	188.22424
Exact Mass	188.116
CAS #	692-04-6
PubChem CID	92832
Appearance	White to off-white solid powder
Density	1.1±0.1 g/cm3
Boiling Point	442.0±40.0 °C at 760 mmHg
Melting Point	250 °C (dec.)(lit.)
Flash Point	221.1±27.3 °C
Vapour Pressure	0.0±2.3 mmHg at 25°C
Index of Refraction	1.490
LogP	-1.42
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	6
Heavy Atom Count	13
Complexity	182
Defined Atom Stereocenter Count	1
SMILES	CC(=O)NCCCC[C@@H](C(=O)O)N
InChi Key	DTERQYGMUDWYAZ-ZETCQYMHSA-N
InChi Code	InChI=1S/C8H16N2O3/c1-6(11)10-5-3-2-4-7(9)8(12)13/h7H,2-5,9H2,1H3,(H,10,11)(H,12,13)/t7-/m0/s1
Chemical Name	(2S)-6-acetamido-2-aminohexanoic acid
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Characterization of a novel enzyme, N6-acetyl-L-lysine: 2-oxoglutarate aminotransferase, which catalyses the second step of lysine catabolism in Candida maltosa. Antonie Van Leeuwenhoek. 1992 Nov;62(4):285-90. [2]. Characterization of a novel enzyme, N6-acetyl-L-lysine: 2-oxoglutarate aminotransferase, which catalyses the second step of lysine catabolism in Candida maltosa. Antonie Van Leeuwenhoek. 1992 Nov;62(4):285-90.

Additional Infomation

N(6)-acetyl-L-lysine is an N(6)-acyl-L-lysine where the N(6)-acyl group is specified as acetyl. It has a role as a human metabolite. It is a N(6)-acyl-L-lysine and an acetyl-L-lysine. It is a tautomer of a N(6)-acetyl-L-lysine zwitterion. N6-Acetyl-L-lysine is a metabolite found in or produced by Escherichia coli (strain K12, MG1655). Acetyllysine has been reported in Drosophila melanogaster, Schizosaccharomyces pombe, and other organisms with data available.

Solubility Data

Solubility (In Vitro)	H2O : ~50 mg/mL (~265.65 mM) DMSO : ~1 mg/mL (~5.31 mM)
Solubility (In Vivo)	Solubility in Formulation 1: 100 mg/mL (531.29 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	5.3129 mL	26.5647 mL	53.1293 mL
	5 mM	1.0626 mL	5.3129 mL	10.6259 mL
	10 mM	0.5313 mL	2.6565 mL	5.3129 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.