Neoantimycin is a GRP78/BiP and K-Ras modulator with anticancer activity. The biosynthesis of neoantimycin is catalyzed by a hybrid nonribosomal peptide synthetase/polyketide synthetase (NRPS/PKS) system.

Physicochemical Properties

Molecular Formula	C36H46N2O12
Molecular Weight	698.76
CAS #	22862-63-1
SMILES	CCC(C)C1C(=O)OC(C(C(=O)OC(C(=O)OC(C(C(C(=O)O1)(C)C)O)CC2=CC=CC=C2)C(C)C)NC(=O)C3=C(C(=CC=C3)NC=O)O)C
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Biosynthesis of the 15-Membered Ring Depsipeptide Neoantimycin. ACS Chem Biol. 2018 May 18;13(5):1398-1406.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	1.4311 mL	7.1555 mL	14.3111 mL
	5 mM	0.2862 mL	1.4311 mL	2.8622 mL
	10 mM	0.1431 mL	0.7156 mL	1.4311 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.