N-Methylindan-2-amine hydrochloride (compound 3b) is an N-alkylated homologue of phenylethylamine that increases hot plate reaction time in mice without inducing dopaminergic effects. N-Methylindan-2-amine hydrochloride can be used to study central noradrenergic mechanisms.

Physicochemical Properties

Molecular Formula	C10H14CLN
Molecular Weight	183.68
CAS #	10408-85-2
Appearance	Solid powder
SMILES	Cl[H].N([H])(C([H])([H])[H])C1([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H]
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Comparison of biological effects of N-alkylated congeners of. beta.-phenethylamine derived from 2-aminotetralin, 2-aminoindan, and 6-aminobenzocyclohepteneJ. Journal of Medicinal Chemistry, 1980, 23(7): 745-749.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	5.4443 mL	27.2213 mL	54.4425 mL
	5 mM	1.0889 mL	5.4443 mL	10.8885 mL
	10 mM	0.5444 mL	2.7221 mL	5.4443 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.