N-(3-Oxobutanoyl)-L-homoserine lactone (3-oxo-C4-HSL) is an autoregulator of carbapenem biosynthesis in Erwinia carotovora ATCC 39048. N-(3-Oxobutanoyl)-L-homoserine lactone induces the expression of rhiI in R. leguminosarum.

Physicochemical Properties

Molecular Formula	C8H11NO4
Molecular Weight	185.18
CAS #	148433-27-6
SMILES	O1C([C@]([H])(C([H])([H])C1([H])[H])N([H])C(C([H])([H])C(C([H])([H])[H])=O)=O)=O
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Autoregulation of carbapenem biosynthesis in Erwinia carotovora by analogues of N-(3-oxohexanoyl)-L-homoserine lactone. J Antibiot (Tokyo). 1993 Mar;46(3):441-54.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	5.4002 mL	27.0008 mL	54.0015 mL
	5 mM	1.0800 mL	5.4002 mL	10.8003 mL
	10 mM	0.5400 mL	2.7001 mL	5.4002 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.