N-(3-Aminopropyl)cyclohexylamine is a cyclohexylamine analogue and a selective inhibitor of spermine synthase, which may be utilized in the study of neurological diseases.

Physicochemical Properties

Molecular Formula	C9H20N2
Molecular Weight	156.27
Exact Mass	156.162
CAS #	3312-60-5
PubChem CID	18718
Appearance	Colorless to light yellow liquid（Density：0.917 g/cm3 ）
Density	0.9±0.1 g/cm3
Boiling Point	238.7±8.0 °C at 760 mmHg
Melting Point	−17-−15 °C(lit.)
Flash Point	112.3±22.0 °C
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.484
LogP	1.27
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	4
Heavy Atom Count	11
Complexity	87.6
Defined Atom Stereocenter Count	0
SMILES	C1CCC(CC1)NCCCN
InChi Key	ITZPOSYADVYECJ-UHFFFAOYSA-N
InChi Code	InChI=1S/C9H20N2/c10-7-4-8-11-9-5-2-1-3-6-9/h9,11H,1-8,10H2
Chemical Name	N'-cyclohexylpropane-1,3-diamine
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: This product requires protection from light (avoid light exposure) during transportation and storage.
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. P J Chu, et al.Antagonistic effect of N-(3-Aminopropyl)cyclohexylamine on neurotrophic action of spermine in primary cultured rat hippocampal and cerebellar neurons. Jpn J Pharmacol. 1995 Dec;69(4):311-5.

Solubility Data

Solubility (In Vitro)	H2O: 100 mg/mL (639.92 mM)
Solubility (In Vivo)	Solubility in Formulation 1: 100 mg/mL (639.92 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	6.3992 mL	31.9959 mL	63.9918 mL
	5 mM	1.2798 mL	6.3992 mL	12.7984 mL
	10 mM	0.6399 mL	3.1996 mL	6.3992 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.