Monoolein is an endogenously produced metabolite.

Physicochemical Properties

Molecular Formula	C21H40O4
Molecular Weight	356.54
Exact Mass	356.292
CAS #	111-03-5
Related CAS #	Monoolein-d5;565183-24-6;Monoolein-d7;2260669-49-4
PubChem CID	5283468
Appearance	White to off-white solid powder
Density	0.9407 g/cm3 (35 ºC)
Boiling Point	483.3±35.0 °C at 760 mmHg
Melting Point	38.5 ºC (acetone )
Flash Point	155.4±19.4 °C
Vapour Pressure	0.0±2.8 mmHg at 25°C
Index of Refraction	1.46384 (589.3 nm 35 ºC)
LogP	6.71
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	19
Heavy Atom Count	25
Complexity	315
Defined Atom Stereocenter Count	0
SMILES	CCCCCCCC/C=C\CCCCCCCC(=O)OCC(CO)O
InChi Key	RZRNAYUHWVFMIP-KTKRTIGZSA-N
InChi Code	InChI=1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h9-10,20,22-23H,2-8,11-19H2,1H3/b10-9-
Chemical Name	2,3-dihydroxypropyl (Z)-octadec-9-enoate
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

Additional Infomation

1-oleoylglycerol is a 1-monoglyceride where the acyl group is oleoyl. It has a role as a plant metabolite. It is a 1-acylglycerol 18:1 and a monooleoylglycerol. It is functionally related to an oleic acid. Glyceryl monooleate has been reported in Nelumbo nucifera and Saposhnikovia divaricata with data available.

Solubility Data

Solubility (In Vitro)

Ethanol: 100 mg/mL (280.47 mM)

Solubility (In Vivo)

Solubility in Formulation 1: ≥ 2.5 mg/mL (7.01 mM) (saturation unknown) in 10% EtOH + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear EtOH stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: 2.5 mg/mL (7.01 mM) in 10% EtOH + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), suspension solution; with ultrasonication. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear EtOH stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. Solubility in Formulation 3: ≥ 2.5 mg/mL (7.01 mM) (saturation unknown) in 10% EtOH + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear EtOH stock solution to 900 μL of corn oil and mix evenly.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	2.8047 mL	14.0237 mL	28.0473 mL
	5 mM	0.5609 mL	2.8047 mL	5.6095 mL
	10 mM	0.2805 mL	1.4024 mL	2.8047 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.