Melanin Concentrating Hormone, salmon TFA (MCH (salmon) TFA) is a 19-amino acid (AA) neuropeptide originally discovered in the pituitary gland of teleost fish, which regulates food intake, energy balance, sleep status, and the cardiovascular system. Melanin Concentrating Hormone, salmon TFA (MCH (salmon) TFA) is a ligand for SLC-1/GPR24 and MCHR2.

Physicochemical Properties

Molecular Formula	C91H140F3N27O26S4
Molecular Weight	2213.50
Related CAS #	Melanin Concentrating Hormone, salmon;87218-84-6
Appearance	Solid powder
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment, avoid exposure to moisture.
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

Targets	SLC-1/GPR24, MCHR2[1]
References	[1]. Identification and characterization of a melanin-concentrating hormone receptor. Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7576-81.ab Disord. 2002 Oct;26(10):1289-95.

Solubility Data

Solubility (In Vitro)	H2O :~25 mg/mL (~11.29 mM)
Solubility (In Vivo)	Solubility in Formulation 1: 100 mg/mL (45.18 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	0.4518 mL	2.2589 mL	4.5177 mL
	5 mM	0.0904 mL	0.4518 mL	0.9035 mL
	10 mM	0.0452 mL	0.2259 mL	0.4518 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.