Mal-L-Dap(Boc)-Osu is an ADC Linker that can be used to synthesize antibody-drug conjugates (ADCs).

Physicochemical Properties

Molecular Formula	C16H19N3O8
Molecular Weight	381.34
CAS #	1703778-79-3
SMILES	O(C([C@H](CNC(=O)OC(C)(C)C)N1C(C=CC1=O)=O)=O)N1C(CCC1=O)=O
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Seattle Genetics, Inc. ADCs with thiol multiplex linkers. World Intellectual Property Organization, WO2020132655 A1 2020-06-25.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	2.6223 mL	13.1117 mL	26.2233 mL
	5 mM	0.5245 mL	2.6223 mL	5.2447 mL
	10 mM	0.2622 mL	1.3112 mL	2.6223 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.