Lucidenic acid O is a terpene compound and a DNA polymerase inhibitor. Lucidenic lactone inhibits calf DNA polymerase-α, rat DNA polymerase-β and HIV-1 reverse transcriptase with IC50 values of 42 μM, 99 μM and 69 μM, respectively.

Physicochemical Properties

Molecular Formula	C27H40O7
Molecular Weight	476.60
CAS #	250643-33-5
SMILES	CC12C(C(CCC(=O)O)=C)CC(O)C1(C)C1C(CC3C(C=1C(=O)C2)(C)CCC(O)C3(CO)C)O
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Lucidenic acid O and lactone, new terpene inhibitors of eukaryotic DNA polymerases from a basidiomycete, Ganoderma lucidum. Bioorg Med Chem. 1999 Sep;7(9):2047-52.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	2.0982 mL	10.4910 mL	20.9820 mL
	5 mM	0.4196 mL	2.0982 mL	4.1964 mL
	10 mM	0.2098 mL	1.0491 mL	2.0982 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.