Limnetrelvir (ABBV-903) is a MPro inhibitor. Limnetrelvir can be used in antiviral research.

Physicochemical Properties

Molecular Formula	C27H23F4N5O4
Molecular Weight	557.50
CAS #	2923500-04-1
SMILES	FC(C1C=C(C#N)C=C(C(N2CCOCC2)=O)C=1N1CC[C@H](C1)NC(C1=CC(NC2C(=CC=CC1=2)F)=O)=O)(F)F
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Progress in Research on Inhibitors Targeting SARS-CoV-2 Main Protease (Mpro). ACS omega. 2024, 9(32), 34196–34219.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	1.7937 mL	8.9686 mL	17.9372 mL
	5 mM	0.3587 mL	1.7937 mL	3.5874 mL
	10 mM	0.1794 mL	0.8969 mL	1.7937 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.