LIMK1 inhibitor 2 (compound 41) is a LIMK1 inhibitor with IC50 of 9 μM.

Physicochemical Properties

Molecular Formula	C10H11N3OS
Molecular Weight	221.28
CAS #	67795-42-0
SMILES	CC1=CC(=NC2=C1C(=C(C(=O)N)S2)N)C
Synonyms	WAY-248134
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Identification of 3-aminothieno2,3-bpyridine-2-carboxamides and 4-aminobenzothieno3,2-dpyrimidines as LIMK1inhibitors. MedChemComm, 2011, 2(10), 977–.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	4.5192 mL	22.5958 mL	45.1916 mL
	5 mM	0.9038 mL	4.5192 mL	9.0383 mL
	10 mM	0.4519 mL	2.2596 mL	4.5192 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.