KSP ligand 1 is a protein ligand targeting KSP (Kinesin) and can be used to synthesize PROTAC KSP-IN-1 for cancer research.

Physicochemical Properties

Molecular Formula	C25H23NO3S
Molecular Weight	417.52
CAS #	1802248-16-3
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Discovery of novel KSP-targeting PROTACs with potent antitumor effects in vitro and in vivo. Eur J Med Chem. 2025 Jan 15:282:117052.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	2.3951 mL	11.9755 mL	23.9509 mL
	5 mM	0.4790 mL	2.3951 mL	4.7902 mL
	10 mM	0.2395 mL	1.1975 mL	2.3951 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.