KIF18A-IN-16 (Compound 15) is a fused-ring KIF18A inhibitor. KIF18A-IN-16 can be used in tumor research (such as colon cancer, breast cancer, and lung cancer).

Physicochemical Properties

Molecular Formula	C30H37N5O4S
Molecular Weight	563.71
CAS #	3033981-01-7
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Fused ring kif18a inhibitor compound, pharmaceutical composition, and preparation method therefor and use thereof. WO2024067675.WIPO, 2023-09-27.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	1.7740 mL	8.8698 mL	17.7396 mL
	5 mM	0.3548 mL	1.7740 mL	3.5479 mL
	10 mM	0.1774 mL	0.8870 mL	1.7740 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.