KC12 is an inhibitor of FOXM1 transcription factor. KC12 exhibits cytotoxicity in cancer cells MDA-MB-231 with an IC50 of 6.13 µM.

Physicochemical Properties

Molecular Formula	C23H17F3N2O3S
Molecular Weight	458.45
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Novel benzothiazole/benzothiazole thiazolidine-2,4-dione derivatives as potential FOXM1 inhibitors: In silico, synthesis, and in vitro studies. Arch Pharm (Weinheim). 2024 Dec;357(12):e2400504.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	2.1813 mL	10.9063 mL	21.8126 mL
	5 mM	0.4363 mL	2.1813 mL	4.3625 mL
	10 mM	0.2181 mL	1.0906 mL	2.1813 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.