Iminostilbene is the chemical precursor of carbamazepine.

Physicochemical Properties

Molecular Formula	C14H11N
Molecular Weight	193.25
Exact Mass	193.089
CAS #	256-96-2
Related CAS #	Iminostilbene-d4
PubChem CID	9212
Appearance	Yellow to orange solid powder
Density	1.1±0.1 g/cm3
Boiling Point	349.1±22.0 °C at 760 mmHg
Melting Point	197 °C
Flash Point	178.4±17.8 °C
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.627
LogP	4.11
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	0
Heavy Atom Count	15
Complexity	222
Defined Atom Stereocenter Count	0
SMILES	N1([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
InChi Key	LCGTWRLJTMHIQZ-UHFFFAOYSA-N
InChi Code	InChI=1S/C14H11N/c1-3-7-13-11(5-1)9-10-12-6-2-4-8-14(12)15-13/h1-10,15H
Chemical Name	11H-benzo[b][1]benzazepine
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: This product requires protection from light (avoid light exposure) during transportation and storage.
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References	[1]. Christian P, et al. Crystallization of Carbamazepine in Proximity to Its Precursor Iminostilbene and a Silica Surface. Cryst Growth Des. 2016 May 4;16(5):2771-2778. Epub 2016 Mar 30.
Additional Infomation	5H-dibenzo[b,f]azepine is a mancude organic heterotricyclic parent that consists of a seven-membered nitrogen hetrocycle fused with two benzene rings. It has a role as a marine xenobiotic metabolite. It is a mancude organic heterotricyclic parent and a dibenzoazepine.

Solubility Data

Solubility (In Vitro)

DMSO: 50 mg/mL (258.73 mM)

Solubility (In Vivo)

Solubility in Formulation 1: ≥ 2.5 mg/mL (12.94 mM) (saturation unknown) in 10% DMSO + 40% PEG300 +5% Tween-80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 + to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	5.1746 mL	25.8732 mL	51.7464 mL
	5 mM	1.0349 mL	5.1746 mL	10.3493 mL
	10 mM	0.5175 mL	2.5873 mL	5.1746 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.