ISO24 (compound 4a) is a potent ligand for Src SH2 with an IC50 of 4.4 mM in a BIAcore assay.

Physicochemical Properties

Molecular Formula	C9H12NO4P
Molecular Weight	229.17
CAS #	473707-40-3
SMILES	CCC1=CC=C(C=C1)NC(=O)P(=O)(O)O
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Small Ligands Interacting with the Phosphotyrosine Binding Pocket of the Src SH2 Protein. Bioorg Med Chem Lett. 2002 May 6;12(9):1295-8.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	4.3636 mL	21.8179 mL	43.6357 mL
	5 mM	0.8727 mL	4.3636 mL	8.7271 mL
	10 mM	0.4364 mL	2.1818 mL	4.3636 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.